The four were in a van near the University of Karachi’s Confucius Institute when the blast ripped through the vehicle on Tuesday evening, Pakistan’s Interior Minister Rana Sana Ullah told CNN.
The Baloch Liberation Army (BLA), a militant separatist group from Pakistan’s southwestern province of Balochistan, claimed responsibility for what it says was a suicide attack in a statement shared with CNN.
A fourth Chinese teacher was injured in the blast, China’s Foreign Ministry said.
“The blood of the Chinese people should not be shed in vain, and those behind this incident will surely pay the price,” the ministry said in a statement.
Pakistan’s Prime Minister Shehbaz Sharif has condemned the incident.
China is a close partner to Pakistan and its biggest source of military and economic support. But in recent years terrorist attacks targeting Chinese nationals and their interests in Pakistan have alarmed Beijing.
Islamabad blamed that attack on the Pakistani Taliban, operating out of Afghanistan. However, there have also been a string of attacks on Chinese nationals and their interests by the BLA, which opposes what it sees as Islamabad’s monopoly over Balochistan’s mineral resources.
Bordering Afghanistan and Iran, Balochistan is Pakistan’s largest but least populated province. It is fundamental to the country’s massive multibillion-dollar infrastructure deal with Beijing, the China-Pakistan Economic Corridor (CPEC).
In 2018, the BLA claimed another attack in which gunmen tried to storm the Chinese consulate in Karachi, killing four people. It said it would not tolerate any Chinese military expansionist endeavors.